Understanding Influenza Mortality and the Effects of Vaccination in the Elderly

Grant number: 566908 | Funding period: 2009 - 2014

Completed

Abstract

We will analyse mortality from influenza and other causes to estimate the numbers of deaths from other causes that are triggered by influenza in elderly persons, and to test the value of vaccination in preventing those deaths. Our results will help to decide whether an expensive clinical trial is really needed to show the benefit of influenza vaccination on all-cause mortality in the elderly.

Related publications (3)

Influenza as a trigger for cardiovascular disease: An investigation of serotype, subtype and geographic location

DC Pearce, JM McCaw, J McVernon, JD Mathews

2017-01-01

Background Seasonal peaks of influenza and cardiovascular disease tend to coincide. Many excess deaths may be triggered by influen..

The influence of changing host immunity on 1918-19 pandemic dynamics

KJ Bolton, JM McCaw, J McVernon, JD Mathews

2014-08-08

The sociological and biological factors which gave rise to the three pandemic waves of Spanish influenza in England during 1918-19..

Understanding mortality in the 1918-1919 influenza pandemic in England and Wales

DC Pearce, PK Pallaghy, JM McCaw, J McVernon, JD Mathews

2011-03-01

Background The causes of recurrent waves in the 1918-1919 influenza pandemic are not fully understood. Objectives To identify the ..

University of Melbourne Researchers

John Mathews

Terry Nolan

James McCaw